The aim of this bi-annual meeting is to discuss ongoing and future developments in the field of integrated structural biology. It will bring together experts from the crystallography, NMR, cryo electron microscopy & tomography and hyper-resolution imaging fields to address key questions in biology, especially around transcription & translation and related mechanisms involving large nucleo-protein complexes. The presentations by leading scientists in the field will have a focus on the technological innovation for multi-resolution approaches to address the structure and function of these complexes at molecular and cellular levels of organization. This time it will be a joint event with the inauguration of a new high-resolution electron microscope (Titan Krios) at the new Centre for Integrative Biology at the IGBMC.

POSTER

Speakers:

- Frédéric Allain, ETH Zürich, Switzerland. Using NMR and EPR to decipher the molecular mechanisms of translation regulation.

- Sacha de Carlo, Eindhoven, The Netherlands. Latest developments in correlative and cryo-TEM workflow solutions.

- Philippe Dumas, IBMC, Strasbourg, France. New developments in ITC to address biological problems.

- Gwyndaf Evans, Oxford, UK. In situ, multi-crystal, high frame-rate: New trends in X-ray crystallography data collection.

- Ignacio Izeddin Aguirre, ENS, Paris, France. Geometry of the nucleus and gene regulation, a single-molecule and super-resolution microscopy approach.

- Bruno Klaholz, IGBMC, Strasbourg, France. Opportunities for future multi-resolution integration at the CBI.

- Andreas Schertel, Oberkochen, Germany. Large volume imaging of cellular ultrastructure using (cryo-) FIB-SEM microscopy.

- Clemens Schulze-Briese, Baden, Switzerland. Hybrid pixel X-ray detectors for advanced life science - applications.

- Holger Stark, MPI Göttingen, Germany. Dynamic macromolecular complexes at high resolution by single particle cryo-EM.

- Sriram Subramaniam, NIH, USA. Imaging cells, viruses and protein complexes with 3D electron microscopy: From structure to mechanism.

- Albert Weixlbaumer, Rockefeller University, USA / IGBMC, Strasbourg, France. Structural basis for transcriptional pausing in bacteria.

Registration to the symposium is free but mandatory. The number of participants is limited.
Deadline for registration May 2014, 25^th

Extension of registration to June 2014, 8th

A poster session will be organized from which 4 posters will be selected for a twelve minutes talk presentation. Poster abstract submission has to be done online after registration.
Deadline for poster abstract submission June 2014, 1^st

Extension for poster abstract submission to June 2014, 8th